Styphnolobium japonicum Lectin (SJA) - Pure
Regular price
$153.18
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SKU# 21510877-1
Product Description
Styphnolobium japonicum agglutinin (SJA) is isolated from Japanese pagoda tree seeds. It has a molecular weight of 133,000 and consists of two subunits. The subunits can be separated into two subfractions, a D-galactose/N-acetyl-D-galactosamine specific lectin (B-SJA-I) and a D-mannose/D-glucose specific lectin (B-SJA-II). SJA has an isoelectric point between pH 4.9 and pH 5.6 and a carbohydrate specificity towards ?GalNAc. This lectin elutes with the sugar GalNAc.
SJA agglutinates all blood group types but has greater affinity for A erythrocytes than of B types, than of O (-SA) types. Binding experiments of the lectin with frozen sections of human kidneys shows specific binding to the endothelia in specimens from blood groups B or AB, thus indicating a D-galactose/N-acetyl-D-galactosamine receptor specificity. SJA lacks mitogenic and immune-suppressive activity.
This product comes in a lyophilized form and is stored at -20ºC. Metal ions calcium and manganese are required for binding.
Technical Specifications
| Molecular Weight | : | 133 kDa |
| Synonyms | : | SJA |
| Shelf Life | : | 2 years |
| Storage Temperature | : | -20°C |
| Hazardous Shipping | : | Non-hazardous |