Ulex europaeus Lectin (UEA I) - Pure
Regular price
$148.00
Sale
SKU# 21510130-1
Product Description
''Ulex europaeus agglutinin (UEA I) is affinity purified isolated from gorse seeds and separated from crude extract by affinity chromatography. It consists of two subunits. The lectin is a glycoprotein that has no mitogenic activity to agglutinates type O erythrocytes, and of a lesser degree to individuals with A2 erythrocytes.
UEA I reacts strongly with ?(1,2) linked fucose residues but poorly or not at all with ?(1,3) or ?(1,6)-linked fucose. UEA I is unable to bind internal fucose structures and the presence of an internal ?(1,3)-linked fucose on the H type 2 oligosaccharide decreases lectin affinity for this blood group antigen by 3-fold.
UEA I has been used as a marker for vascular endothelium and used to identify endothelial cells of benign vascular lesions more specifically than antibodies Factor VII-related antigen. UEA I coated magnetic beads have been used to isolate endothelial cells associated with micro-vessels for subsequent cell culture. This lectin has also been used to differentiate between angiosarcomas and epithelial tumor.
Technical Specifications
| Molecular Weight | : | 63 kDa |
| Synonyms | : | UEA I |
| Shelf Life | : | 2 years |
| Storage Temperature | : | -20°C |
| Hazardous Shipping | : | Non-hazardous |